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Subjects who complied with the screening criteria were briefed on the study protocol and gave written informed consent to participate in the study

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In three separate sessions, study participants underwent two MRI exams, one before and one after each of the following smoking/vaping episodes: tobacco cigarette, e-cigarette aerosol with nicotine and e-cigarette aerosol without nicotine

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Some anti-tobacco activists complained that tobacco industry lobbyists had succeeded in watering down several proposals