how the tobacco industry targets youth Restored CDC | and Use | Smoking and Tobacco Use The Illusion of Safety: Unmasking

As your saliva moistens the pouch, nicotine is released and taken up by blood vessels under the lining of the mouth over several minutes

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Further, smoking rates among low-income adults have fallen more slowly than among higher earners declining by just 1.6 percent annually between 2003 and 2023, compared to a 2.6 percent annual decline among adults earning $50,000 or more

The buccal route has always been the most advantageous route for nicotine administration since the drug can reach the systemic circulation without being degraded by gastrointestinal and hepatic first-pass metabolism (56,57)