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Like Marlene Dietrich with her cigarette holder, or James Dean I suspect that this whole cigarettes-looking-sexy business started with the early ads, which featured coquettish and beautiful women inviting one to buy cigarettes or rolling paper

The "It's Toasted" slogan was also a real slogan for them.

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GPR15, previously reported to direct regulatory T (Treg) cell colon homing, was upregulated in the colon tissues of both chemically induced colitis models after smoke exposure

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