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23,61 p73 turnover was also regulated post-translationally by Pirh2 and Itch/AIP4, but not by Mdm2 and Cop1

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Contraindications include active infection at the injection site, severe thrombocytopenia, or anticoagulation therapy requiring provider clearance

p53 controls both apoptosis and senescence by promoting p21 transcription, resulting in cell cycle arrest during DNA repair