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Biological activity of the endocannabinoid system Once in the body, 9 -THC and CBD exert their effects via the endocannabinoid system (ECS).The identification of the specific binding sites for 9 -THC in the brain [45], complemented by the cloning of the cannabinoid receptor 1 (CB1), that led to the development of the concept of a cannabinoid receptor system given the binding of 9 -THC to CB1 as a partial agonist [46]

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This reduces the functioning of the kidney

METZ, E

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The presence of nicotine is clearly not the whole story. The authors said a possible weakness in the findings, published in Nicotine And Tobacco Research, may be that people are not accurately recalling their smoking history