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and acuteor, with frequent or repeated use, chronicalterations of the hormonal, cardiac, gastrointestinal, and central nervous systems

In France, these indications of the so-called nicotine, tar and CO content disappeared in 2016 when plain packaging was introduced for all tobacco products, because studies had shown that they misled consumers about the real content of these substances in cigarettes

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E-cigarettes were developed to aid those struggling to quit smoking

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18 mg/mL) [8], which equates to a content ~ 22% higher than that indicated in the product label