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In addition, while asymptomatic nonsmokers had a plateau phase over which lung function remained stable, smokers did not

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Although combustion of cigarette produces CO and nicotine that are immunosuppressive, we think that the amount of CO and nicotine inhaled during smoking may not be sufficient to suppress vigorous allograft rejection

A great way to prevent this is to smoke at a slower pace

Funding This study was supported by Grant 81770025 from National Natural Science Foundation of China, Grant ZH2018QNA48 from Cross research funds of Translational Medicine and Grant 2017ZZ02014 from Shanghai key discipline for respiratory diseases