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Many adults have smoked menthol-flavoured cigarettes for decades

Further, nicotine administration results in increased fibronectin (FN1) gene expression in rat hearts [105]

Addict Biol 2017

Because the window of detection for nicotine is relatively short (approximately 2 hours), cotinine extends the window of detection for several days and is the preferred method of screening for tobacco use

Smoking costs the United States almost $170 billion in direct medical care for adults and over $156 billion in lost productivity due to exposure to secondhand smoke and premature death

it's a fundamental change in how the world perceives vapingfrom a nicotine delivery system to a flavor-focused, lifestyle experience