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The researchers specifically investigated whether cannabis use was associated with adverse cardiovascular outcomes among the general adult population, among people who had never smoked tobacco or used e-cigarettes, and among younger adults (defined as men under age 55 and women under age 65) at risk for heart disease

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And they are especially concerned about refill cartridges because of toxins

When smoke is drawn through the filter, the charcoal adsorbs (not absorbs) the harmful compounds, including: Tar: A sticky, carcinogenic substance that coats the lungs

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