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Bismuth is contraindicated in patients with an aspirin allergy, history of GI bleed, history of coagulopathy, active influenza, or chicken pox infection due to the risk of developing Reye's syndrome

a recent survey showed use increased among high-schoolers from 1.5% to 16% between 2011 and 2015, with about 3 million middle- and high-schoolers reporting e-cigarette use in 2015

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The company committed $30 million for youth prevention efforts, including distributing educational materials to retailers and conducting research into technologies to prevent youth sales

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