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CBD can be an option for managing insomnia, chronic pain and anxiety, although more research is required

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Of note, another study indicated that although RANTES/CCL5 and CCR1 mRNA were upregulated in flavour/nicotine-containing e-cigarette users, vaping flavour and nicotine-less e-cigarettes did not significantly dysregulate cytokine and inflammasome activation [43]

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Acknowledgements The authors thank Cambustion Ltd