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These antibodies trigger the release of histamine from mast cells, which in turn triggers the allergy symptoms of sneezing, sniffing, and so on

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Because our sample was modest, the case mix was heterogeneous, and the outcomes were self-reported, larger multicentre investigations with standardized protocols and more detailed measures of smoking exposure are needed to validate and refine these conclusions

Mirbolouk, M., Charkhchi, P., Orimoloye, O

It is used, for example by clinicians, as a parameter for eligibility to screening for lung cancer

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