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The compound was developed in the late 1990s by Novo Nordisk and characterised in a 1998 paper as the first selective GH secretagogue, meaning it stimulated GH release without the prolactin, ACTH, cortisol, or aldosterone elevations seen with earlier GHRPs

Immunohistochemical localization of the acylases that catalyze the deacetylation of N-acetyl-L-cysteine and haloalkene-derived mercapturates

The Social Responsiveness Scale, second edition (SRS-2) adult self-report form was used to assess the severity of ASD-related symptoms [39]

Most of PD cases are sporadic and only a minor subset of overall PD cases is associated to be familial 4,5

A recent review has documented this synergy (McGuire et al., Curr Rev Musculoskelet Med 2025)