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Most commonly this is between 60 and 100 mg

Alongside their pencils business, the firm specialised in small silver novelties such as letter openers, bookmarks, decanter labels, pin cushions, inkwells and cigar cutters

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For lung cancer and COPD, however, there was little difference in risk estimates between male and female smokers, providing support for the notion that women appeared to be more susceptible to lung diseases associated with smoking, due probably to potential protective role of oestrogen in these diseases and the anti-oestrogenic effects of tobacco smoke

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Over time, this added strain can weaken the heart and may even lead to heart failure