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I highly recommend reading Proctor (2012) for further information, but in general the scientific evidence from the 1930s to the 1950s was accumulating in four areas of research: Population studies people who smoked had higher rates of lung cancer Animal studies tobacco caused tumors in model organisms Cellular pathology cigarette smoke was shown to deaden the hairlike cilia in the lungs upper airway Cancer-causing chemicals in cigarettes cigarette smoke contained polycyclic aromatic hydrocarbons (PAHs), which had been previously shown to cause cancer in people exposed to coal tar Multiple lines of evidence converging like this, linking a health effect with a specific factor, is one of the important ways that epidemiologists assess whether an exposure like smoking a cigarette can cause a detrimental health outcome

PLoS One 9, e115899 (2014), Abstract Gender dimorphism in regulation of plasma proteins in streptozotocin-induced diabetic rats: J.W

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"Every time taxation is increased on tobacco it loses the Treasury millions that could have been spent on public services," said its director general Giles Roca

So the bottom line is clear - while cutting down has some benefit, to really reduce your risk of complications associated with cigarette smoking, you need to stop completely