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The other model instead added a continuous covariate for time, as measured by the number of years between period midpoints relative to the first period, and produced a p-value from a t-test to assess a linear ANA time trend

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Notably, however, treatment of SV-HUC cells with BCEVs resulted in extremely significant increases in the release of monocyte chemotactic protein 1 (MCP-1), and this upregulation was even more pronounced when these urothelial cells were treated with CSE- or MEL-induced BCEVs (Fig

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