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Refueling a gasoline or diesel car takes three to four minutes, so that next cigarette can certainly wait until the smoker reaches a safer zone where there isn't a fire hazard

The difference can be explained by the fact that Dewar and colleagues measured mitochondrial respiration only in the presence of succinate as OXPHOS substrate

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However, among those who continued to smoke, the average daily cigarette consumption initially decreased but then showed an increasing trend in the later part of the study period, suggesting a potential hardening of smoking among a smaller proportion of older adults