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3 p = 0.00004, ***

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Additionally, a recent study demonstrated that in T2DM-associated fatty liver disease, activating SIRT1 deacetylates PGC-1, improving mitochondrial function, promoting FAO, and reducing hepatic lipotoxicity [42]

This schematic illustrates (left) the mechanism of action of edrophonium as a short-acting, reversible acetylcholinesterase (AChE) inhibitor that prevents acetylcholine breakdown at the neuromuscular junction

M., Hong, S.-T