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People who have MS and smoke tobacco may also be more likely to have greater demyelination, more lesions or plaques, and more extensive brain damage than those with MS who do not smoke and are not exposed to secondhand smoke

The active ingredient in cigarettes, nicotine, activates the release of hormones which lead to these effects

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doi: 10.1038/srep25599 (2016)

However, the Trump Administration refused to back the bill, on the basis that it contains provisions that are unsupported by the available evidence regarding harm reduction and American tobacco use habits and that, furthermore, the Bill may restrict access by adult e-cigarette users to products that may provide a less harmful alternative to traditional cigarettes

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