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By bridging epidemiological evidence with mechanistic insights, this work advances our understanding of how cigarette smoke interacts with genetic regulators to affect immune responses and sheds new light on the complexity and heterogeneity underlying IBD pathogenesis

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The 2020 Keep America Beautiful survey estimates that the actual number of cigarette butts polluting our environment is closer to 9.7 billion cigarette butts polluting roadways and waterways combined , along with 392 million pieces of other tobacco-related products and packaging, making up nearly 20% of all U.S