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Studies focusing on the use of TBV for human infectious diseases were searched in PubMed, Google Scholar, and science direct from 1995 to 2021 using the keywords Tobacco-based vaccines OR transgenic tobacco OR Nicotiana benthamiana vaccines AND Infectious diseases or communicable diseases

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Tobacco cultivation is promoted to farmers as a profitable venture, although recent years have seen increased costs of production along with declining global prices for tobacco

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