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Several extensive cohort-based studies have found that cardiovascular disease risk factors such as tobacco smoking are associated with cognitive decline and increased risk of dementia in older age 6

Gallus and his colleagues recently published a review of 26 studies on the use of heated tobacco products conducted around the world since 2022

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However, people taking a high dose of the drug (40 mg or more per day) may have an increased risk of side effects

This included patients who were in the ICU, in the throes of a heart attack or right after bypass surgery