Evidence supporting the causal relationship of both passive and active exposure to tobacco smoke with the development of atherosclerosis and cardiovascular morbidity, beginning as early as fetal life, has been found in a wide array of studies, including those using direct measurement of atherosclerosis in humans and animals, noninvasive measurement of injury to cardiovascular end organs, and measurement of associations with biomarkers known to be associated with atherosclerosis and other forms of cardiovascular disease
Research has shown that social support increases tobacco cessation success and maintenance of a tobacco-free lifestyle
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A 2019 literature review noted evidence that nicotine hijacks the developing brain and nAChRs and can act as a gateway drug to using other addictive substances, such as cocaine. Symptoms of nicotine addiction can appear in teens within days to weeks of starting smoking. If they stop using nicotine, they will experience withdrawal symptoms, such as Nicotine cravings Feeling anxiety or depression Irritability Restlessness Sleeping problems Problems concentrating Its common for people to keep using nicotine products to relieve these symptoms