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Today about 19% of Americans smoke, down from over 40% a few decades ago

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Analysis of acrolein-derived 1, N -propanodeoxyguanosine adducts in human leukocyte DNA from smokers and nonsmokers

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Smoking activates the lymphocytes and increases the autoimmune activity, which is already set in the patients and it leads to the flare up of disease in the smokers

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