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A 2019 study found sublingual B12 supplements (aka the kind you put under your tongue) were even more effective than B12 shots

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Third, mitochondrial support

Different species and even strains metabolize compounds differently, requiring species-specific adjustments to the 5-Amino-1MQ dosage

By inhibiting NNMT, 5-Amino-1MQ reduces 1-MNA formation and alleviates the methyl sink, increasing SAM availability for other methylation reactions, while freeing nicotinamide for recycling through NAMPT toward NAD