Furthermore, Medscape recently reported in June of 2025 on a meta-analysis of 24 relevant studies investigating cannabis use and found that marijuana use was associated with a twofold increased risk for major adverse cardiovascular events including death, stroke and myocardial infarction
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[51] Michael LaFaive et al., Cigarette Taxes and Smuggling: A Statistical Analysis and Historical Review, Mackinac Center for Public Policy, 2008, 18, [52] William Orzechowski and Robert Walker, The Tax Burden on Tobacco: Historical Compilation Volume 59, 2024 (Orzechowski & Walker, 2025), 12