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Zhai 12 conducted a single-center retrospective study in China and reported that heavy smokers had lower UC severity than other smokers and nonsmokers based on the Modified Mayo score, and that current smokers needed fewer corticosteroids than nonsmokers

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By 2025, the estimated number of smokers in the UK is projected to be around 13% of the population or 8 million adults (aged 18 years and above) which is comparable to the US