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These might include: panic psychosis confusion anxiety paranoia delusions hallucinations nausea and vomiting red eyes delayed reaction times reduced muscle and limb coordination increased heart rate distorted senses People who do not use cannabis regularly are more likely to experience these unpleasant effects from being high

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Conditional recommendations are made when the certainty of evidence is lower, when the margin between desirable and undesirable consequences is small and the balance depends on patient values and preferences, or when there is high variability in the values and preferences of patients

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