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The costs involved in preparing pre-market applications are too high for the vast majorities of independent e-cig companies, and by effectively removing all devices introduced to the market after February 2007, the FDA is forcing small players to compete with Big Tobacco in the cigalike sector

The problem is twofold

Obesity and pregnancy place added pressure on the upper abdomen

American Journal of Health Behavior, 44(5) , 732-743

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