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2 Materials and methods 2.1 Experimental animals This study comprised adult male C57BL/6 mice (aged 810 weeks) weighing 2228 g (Shanghai Jihui Experimental Animal Breeding Co., Ltd.), which were housed for at least 1 week in advance in an animal room with alternating cycles of 12 h of light and 12 h of darkness (lights on at 7:00 a.m

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The government essentially has three tools to moderate consumption: ban the item that is causing the problem, add regulations that make it more difficult to acquire the product (think age requirements to purchase tobacco or alcohol), or use taxation to make the product more expensive to curtail consumption

Association of menthol-flavoured cigarette smoking with all-cause and cause-specific mortality risk

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Anderson AE, Hure AJ, Forder PM, Powers J, Kay-Lambkin FJ, Loxton DJ (2014)