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Freezing a mixed multi-use vial can create solution changes and freeze-thaw stress that are not worth accepting unless a protocol specifically requires aliquoted frozen storage

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In cases of pregnancy, pregnant subjects should take caution while using bacteriostatic water in any form due to the lack of animal focused research studies regarding how the benzyl alcohol may or may not have negative effects on the fetus or the reproductive system

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Certain medications, including some blood pressure drugs and cholesterol-lowering agents, can cause muscle pain or fatigue

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When NNMT activity is reduced, less nicotinamide is methylated and wasted, allowing NAD pools to remain higher

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