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New York: Simon & Schuster, 1990

A 2021 study found that approximately 3% of individuals required recurrent hospitalization within 90 days for pneumonia, and about 9% required it within a year

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In advanced COPD, hypoxia plays the primary role in producing pulmonary hypertension, both by causing vasoconstriction of the pulmonary arteries and by promoting remodeling of the vessel wall (either by inducing the release of growth factors 107 or as a consequence of the mechanical stress that results from hypoxic vasoconstriction)