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One of the primary mechanisms responsible for the anti-inflammatory properties, is the upregulation of endothelial vascular protective functions, mediated by endothelial cell nitric oxide synthase and a subsequent rise in NO bioavailability [131]

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In Connecticut, clinics like CT Addiction Medicine provide the awareness and knowledge to the patients regarding these parameters to help them choose wisely and get an appropriate treatment when the need arises

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However, they are subject to the same rules as tobacco products