The most pervasive structural threat is the ongoing long-term decline in cigarette consumption in high-income markets, driven by successful tobacco control policies, increasing health consciousness, the proliferation of alternative nicotine products, and rising real prices resulting from excise tax escalation
3a and Supplemental Fig
Acknowledgements The authors would like to thank Oriane Strassel for her help with data pre-processing and absolute quantification, and Marie-Anas Monat for her technical support during sample preparation
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This ex-vivo generation of pro-inflammatory cytokines may be related to the higher levels of oxidative stress reported in cigarette smokers 42,43
Michael's Hospital and the Canada Research Chair programme
