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Moreover, it stands as a bulwark against the strain tobacco-related illnesses place on our healthcare system
Australian smokers face an additional 12.5% tax increase each year for the next three years
Today, plenty of celebrities have managed to quit the habit and live the smoke-free dream

Therefore, this group of diseases is grouped under the name epidermal differentiation disorders (EDD).1 The epidermis is a tissue with a very well-demarcated structure: the constantly dividing stem cells responsible for regenerating the epithelium (keratinocytes) are located in the stratum basale and the cells generated from this division undergo a gradual process of differentiation as they migrate toward the surface.2 This differentiation process (called cornification) causes morphological changes in keratinocytes due to changes in protein expression patterns, reorganization of the cytoskeleton, lipid secretion, and establishment of intercellular junctions, culminating in the formation of the stratum corneum, which is the most superficial layer of the epidermis, in which keratinocytes have terminally differentiated into corneocytes, cells lacking nuclei and organelles whose cytoplasm is completely filled with structural proteins

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