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Originally, e-cigarettes were created as a smoking cessation tool for adults addicted to cigarettes

Overall, the lighter is fairly detailed but still slightly simplified to make the tutorial easier for beginners

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Sensitivity analyses showed that participants who died within a short period of time had little effect on the results of the Cox proportional regression model and the multivariable RCS model, suggesting that the correlation between folate/vitamin b12 and mortality was not confounded by reverse causal effects ( Supplementary Table S1 , Supplementary Figure S1 )

But the survey may simply have measured effects over too short a duration