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In terms of receptor expression, MCs are traditionally characterized by high levels of FcRI, the high-affinity Immunoglobulin E (IgE) receptor that mediates type I hypersensitivity responses and plays a key role in initiating allergic inflammation in AD (67, 68)

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The health benefits far outweigh any concerns about their negligible nicotine content

This was observed in a combined analysis of nine randomized studies (2230) and one prospective study (31) which investigated the short-term effects of e-cigarettes on healthy subjects, both with and without a history of tobacco use

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