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The clinical significance of these nonclinical findings is not known, and healthcare providers should balance the benefits of appropriate anesthesia in pregnant women, neonates, and young children who require procedures with the potential risks suggested by the nonclinical data (see WARNINGS, Pediatric Neurotoxicity, PRECAUTIONS, Pregnancy, and Animal Toxicology and/or Pharmacology)

Chemo, no matter how you cut it, is hell on wheels," he said

"The game amuses medangerous though it isand I shall stay as long as I can," he wrote in another letter

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