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And that's the concern with pluripotency

The hypothalamic-pituitary-adrenal and the GH/IGF-I axis are also closely associated, as cortisol is required for physiological GH secretion

Accordingly, agents targeting the molecular participants in the Th2-high subtype (e.g., anti-IL-4, anti-IL-5, anti-IL-13, IgE blockers, and inhibitors of prostaglandin D2 (CRTH2) receptor) have recently been presented as potential drugs to treat asthma

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J Transl Med (2023) 21(1):259