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We acknowledge that our model does not completely mimic COPD in humans in that it does not induce significant functional changes, however it provides a useful tool for elucidating HRV-induced exacerbations in the context of long-term cigarette smoking, the researchers wrote

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CT Guangdong has four cigarette factories all in Guangdong provice (Guangzhou, Shaoguan, Meizhou, and Zhanjiang), with total assets in excess of US$1.59 billion

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