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[Google Scholar] Suchowerska AK, Stokman G, Palmer JT, Coghlan PA, Pieterman EJ et al

125,126 TTX-MC138 (NCT06260774 and NCT05908773), designed by TransCode Therapeutics, targets microRNA-10b in the treatment of pancreatic cancer

The N-terminal GSDMD fragment creates transmembrane pores, leading to the initiation of pyroptotic cell death

532 Another candidate, ultevursen (QR-421a), is an ASO therapy for treating vision loss in patients with pigmentary retinopathy due to mutations in exon 13 of the USH2A gene

47 Sterile inflammation APAP-induced liver toxicity may trigger extensive sterile inflammation in the liver tissue

doi: 10.1038/ni.3796 18 KnottSRVWagenblastEKhanSKimSYSotoMWagnerMet al