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Hyperuricemia continues to be inadequately managed, primarily due to factors such as ineffective dosing of urate-lowering therapy, patient noncompliance, and intolerance/adverse events associated with current treatment options

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30 SD rats were randomly divided into 5 groups (6 rats/ group): control group, COPD model group, AZI low-dose (25 mg/kg) group, AZI middle-dose (50 mg/kg) group and AZI high-dose (100 mg/kg) group

Mayer M, Reyes-Guzman C, Grana R, et al