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2004 Surgeon General's ReportThe Health Consequences of Smoking (PDF)

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They also tend to use e-liquids with high nicotine levels

Since Im already on the subject, acidic smoke causes nicotine to be absorbed less readily, and tobacco that is higher in sugar produces a more acidic smoke, so strains such as Virginia work well for cigarettes as the lower nicotine content and acidic smoke allow inhalation with less harshness and discomfort