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Thus, following the harvest the tobacco farmer has to apply a complicated procedure to dry out the leaves which is almost like the natural process but strictly monitored, and curing is only the first stage

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Improved extraction methodologies and ancient residue metabolomics techniques developed by Brownstein and colleagues (Reference Brownstein, Tushingham, Damitio, Nguyen and Gang2020) have been applied to a large sample of archaeological materials from western North America