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(6) Complex I: Complex I (NADH:ubiquinone oxidoreductase) is a large multiprotein complex located in the mitochondrial inner membrane that accepts electrons from NADH and transfers them to ubiquinone (CoQ 10 ) via FMN and a series of ironsulfur (FeS) clusters, reducing it to ubiquinol (CoQ 10 H 2 ) 68,69

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5.2 Animal models In animal models of Cushings syndrome and associated obesity, the simplest model is the excessive administration of exogenous GCs to rodents by s.c., i.p., i.m

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A: The key difference is half-life and dosing frequency