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At low concentrations, it is a weak inducer of CYP3A4, but at therapeutic levels shows inhibitory properties, suggesting the potential for both auto-induction and inhibition depending on the concentration (Shimokawa et al., 2015)

"I think that the initiative is very important as well as overdue, but the barrier parts of it certainly have struck me with respect to this," Neal said

According to the NIH, EVALI can be fatal, causing 68 deaths as of 2023

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