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Adav, S

153 When aggravated ROS production by exogenous stimuli such as lipopolysaccharide is achieved, the activation of inflammasome will be stimulated and lead to cell damage

Radiotherapy exerts its tumor-killing effects through two main mechanisms: i) Direct DNA damage induced by high-energy radiation

Sankaranarayanan S, Jamshed M, Samuel MA

Non-mammalian models such as zebrafish and Drosophila are well-established platforms for studying the biological effects of xenobiotics, owing to their high genetic similarity to humans

This disrupts the ionic balance inside and outside the cell, increases membrane permeability, impairs the exchange of substances across the membrane, and ultimately leads to the death of tumor cells