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In vitro studies have inconsistent findings, which is likely due to use of various flavorants and different types of cells studied, as some e-cigarette aerosol chemicals have been found to be pro-inflammatory while others have anti-inflammatory effects, with different cells having different responses to the same aerosol(25)

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Arch Toxicol 96: 33633371, 2022

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The domestic cigarette industry continues to reel under the pressure of increased indirect taxes, the company said in its annual report (pdf), citing a decline in volumes and a 4.2% growth in revenue in 2014-15

Because of this, you can start by using the same dose of CBDa as you would of CBD