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"Health Inequalities: Historical and cultural roots of tobacco use among Aboriginal and Torres Strait Islander people"

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Nicotine Replacement Therapy (NRT) : Products providing nicotine without tobacco's harmful chemicals, used for smoking cessation

There is evidence that mitochondrial ROS concentrate locally and lead to activation of the caspase-independent cell death program, apoptosis inducing factor-mediated cell death, and/or necrotic cell death

Smoking increases the production of reactive oxygen species (ROS) in the body, leading to oxidative stress