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The penalties for not complying with the Regulations when they come into force are set out under Part VI of the TVPA

In addition, a series of inflammatory response genes were upregulated, with notably, the genes coding for the pro-inflammatory interleukin 1A, 1B and 6, together with the IL1RN agonist and IL-1 receptor IL1RL1

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Reduced toxicant yields in mainstream smoke The effect of split-tipping on toxicant yields in mainstream smoke was measured for both volatile and condensed phase toxicants under two machine smoking regimes (ISO, and a higher flow rate 60/2/30 VO smoking regime)

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